Amyloids-DNA complexes mediate adherence and cohesiveness of bacterial biofilms
نویسنده
چکیده
Complexity of bacterial biofilms is generally due to their composition in terms of microorganisms as well as in the diversity of their matrix components. The commonly described extracellular polymeric substances (EPS) are exopolysaccharides (ePS), exoproteins (ePN) and extracellular DNA (eDNA). Besides, several studies have shown that the ePN are the most abundant compound within a biofilm [1]. Very recently eDNA and ePN, among which amyloid fibrils (AF), have been shown to play crucial roles in biofilm adhesion, cohesiveness and resistance properties [2, 3]. Moreover several enzymes were shown to be efficient in reducing biofilms, particularly DNAse or proteases.
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